Effect of Virogenic Hydroxylamine-Metabolites on Deoxyribonucleic Acid and RNA-Polymerase

نویسندگان

  • Hirohisa Omura
  • Satoru Iiyama
  • Takato Fujii
  • Kazuo Yamafuji
  • H. Omura
چکیده

Single strand scission in duplex DNA is caused by hydroxylamine, Na-nitrite or oximes of glucose and galactose of proper low molarities. The suitable nicking in the DNA-molecule brings about the elevation of its template nature. Excessive breakage of DNA, however, reduces its template activity. The results have been discussed in relation to an effect causing cyto-differentiation and -anomalization.

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تاریخ انتشار 1998